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而在刚刚过去的2025年,体内CAR-T更是成为巨头竞相押注的又一大方向。2025年3月,阿斯利康斥资10亿美元价格收购体内CAR-T细胞疗法开发公司EsoBiotec,主要针对肿瘤和自免疾病;6月,艾伯维以21亿美元收购Capstan,看中的正是体内CAR-T疗法CPTX2309治疗自免疾病的潜力;今年2月,礼来24亿美金入局体内CAR-T,收购Orna Therapeutics,后者的核心管线同样是治疗自免疾病的体内CD19 CAR-T疗法。

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Apple unveils M5 Pro and M5 Max chips with new ‘Fusion Architecture’